Water absorption of mid-infrared (MIR) radiation severely limits the options for vibrational spectroscopy of the analytes – including live biological cells – that must be probed in aqueous environments. I will describe a live cell biosensing platform based on arrays of plasmonic metasurfaces.
Heart valve disease (HVD), a significant complication of cardiovascular disease, is one of the leading global causes of death. HVD can be treated using medical devices such as artificial valves, stents, and patches.
Collective cell dynamics play a crucial role in many developmental and physiological contexts. While two-dimensional (2D) cell migration has been widely studied, how three-dimensional (3D) geometry and topology interplay with collective cell behavior to determine dynamics and functions remains an open question.
With this study, Dr. Kravets and her team is testing hypotheses that a) subpopulations of insulin-producing β-cells (1st responder β-cells) drive response to glucose, and b) immune cells in Type 1 Diabetes may be preferentially interacting with 1st responder β-cells.
When we think about bacteria we normally think about disease causing bacteria and how we eradicate them with cleaners and antibiotics. But bacteria aren't all bad. In my lab we study how we can use bacteria to improve human health and the environment.
Magnetic fields offer the possibility of manipulating objects from a distance and are ideal for medical applications, as they penetrate human tissue without inflicting any harm on the patient.
Collagen damage is associated with many pathologic conditions (e.g. tumor, fibrosis, arthritis) and musculoskeletal injuries (e.g. tendonitis). Therefore, the ability to specifically target damaged and denatured collagens (over intact collagen) could lead to new diagnostics and therapeutics, as well as applications in regenerative medicine.
Addressing fragility fractures, prevalent in aging, osteoporosis, and diabetes, poses a persistent challenge in clinical practice. While the fracture mechanisms in engineering materials are well-established, understanding bone remains complex.
Many people are faced with paralysis, amputation or other conditions that present important challenges in tasks of daily living. In addition, many workers are regularly faced with dangerous or challenging physical work environments, such as in manufacturing plants or in space.
